Is it prudent to brush my teeth prior to applying whitening strips? This seemingly simple question leads to a labyrinth of considerations, doesn’t it? On one hand, a good brushing can eliminate debris and plaque, creating a pristine canvas for the whitening agents to penetrate effectively. However, could this preemptive measure inadvertently cause sensitivity? After all, the abrasiveness of toothpaste and mechanical action of brushing may expose dentin, making teeth more vulnerable to the harsh chemicals contained in whitening strips. Moreover, would the type of toothpaste used—be it fluoride-rich, bleaching, or sensitive—alter the efficacy of the whitening process? What if the residue from the toothpaste interferes with the adhesive qualities of the strips? One can’t help but wonder if there exists a universally accepted practice in this realm, or if the answer is as elusive as the perfect shade of white we’re all chasing after. What factors should weigh into this decision to cultivate optimal results?